首页> 外文OA文献 >Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1):an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid excretion in patients with alkaptonuria after 4 weeks of treatment

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Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1):an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid excretion in patients with alkaptonuria after 4 weeks of treatment

机译：尼替尼酮在碱性磷酸酶尿症1（SONIA 1）中的适用性：一项国际性，多中心，随机，开放标签，无治疗对照，平行组，剂量反应研究，研究每日一次尼替尼酮对24小时尿尿酸的影响治疗4周后的蛋白尿患者排泄

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Ranganath, Lakshminarayan R; Milan, Anna M; Hughes, Andrew T; Dutton, John J; Fitzgerald, Richard; Briggs, Michael C; Bygott, Helen; Psarelli, Eftychia E; Cox, Trevor F; Gallagher, James A; Jarvis, Jonathan C; van Kan, Christa; Hall, Anthony K; Laan, Dinny; Olsson, Birgitta; Szamosi, Johan; Rudebeck, Mattias; Kullenberg, Torbjörn; Cronlund, Arvid; Svensson, Lennart; Junestrand, Carin; Ayoob, Hana; Timmis, Oliver G; Sireau, Nicolas; Le Quan Sang, Kim-Hanh; Genovese, Federica; Braconi, Daniela; Santucci, Annalisa; Nemethova, Martina; Zatkova, Andrea; McCaffrey, Judith; Christensen, Peter; Ross, Gordon; Imrich, Richard; Rovensky, Jozef;
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1. Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid excretion in patients with alkaptonuria after 4 weeks of treatment [J] . Ranganath Lakshminarayan R., Milan Anna M., Hughes Andrew T., Annals of the Rheumatic Diseases: A Journal of Clinical Rheumatology and Connective Tissue Research . 2016,第2期

机译：尼替尼酮在碱性磷酸酶尿症1（SONIA 1）中的适用性：一项国际性，多中心，随机，开放标签，无治疗对照，平行组，剂量反应研究，旨在研究每日一次尼替尼酮对24小时尿尿酸的影响治疗4周后的蛋白尿患者排泄
2. The effect of nitisinone on homogentisic acid and tyrosine: a two-year survey of patients attending the National Alkaptonuria Centre, Liverpool [J] . Milan Anna M., Hughes Andrew T., Davison Andrew S., Annals of clinical biochemistry. . 2017,第3期

机译：核酮对甲酸和酪氨酸的影响：LIVERPOOL全国alaptonuria中心患者的两年调查
3. Clindamycin phosphate 1.2%-benzoyl peroxide 3.0% fixed-dose combination gel has an effective and acceptable safety and tolerability profile for the treatment of acne vulgaris in Japanese patients: a phase III, multicentre, randomised, single-blinded, active-controlled, parallel-group study [J] . Kawashima M., Hashimoto H., Saenz A. B. Alio, British Journal of Dermatology . 2015,第2期

机译：磷酸克林霉素1.2％-过氧化苯甲酰3.0％固定剂量组合凝胶在日本痤疮的治疗中具有有效且可接受的安全性和耐受性：III期，多中心，随机，单盲，主动控制，平行小组学习
4. Assessment of the Effect of Once Daily Nitisinone Therapy on 24-h Urinary Metadrenalines and 5-Hydroxyindole Acetic Acid Excretion in Patients with Alkaptonuria After 4 Weeks of Treatment [O] . A. S. Davison, B. Norman, A. M. Milan, 2018

机译：评估治疗4周后每日一次尼替尼酮治疗对碱度尿症患者24小时尿中肾上腺素和5-羟吲哚乙酸排泄的影响
5. Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid excretion in patients with alkaptonuria after 4 weeks of treatment. [O] . Ranganath LR, Milan AM, Hughes AT, 2016

机译：Nitisinone在alkaptonuria 1中的适用性（sONIa 1）：一项国际性，多中心，随机，开放标签，无治疗对照，平行组，剂量反应研究，以研究每日一次的nitisinone对24小时尿中尿黑酸的影响治疗4周后患有尿潴留的患者排泄。

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